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・ Aminoalkylindole
・ Aminoallyl nucleotide
・ Aminobacter
・ Aminobacter aganoensis
・ Aminobacter aminovorans
・ Aminobacter anthyllidis
・ Aminobacter ciceronei
・ Aminobacter lissarensis
・ Aminobacter niigataensis
・ Aminobenzoate decarboxylase
・ Aminobenzoic acid
・ Aminobutyraldehyde dehydrogenase
・ Aminobutyrate aminotransferase
・ Aminobutyric acid
・ Aminocandin
Aminocaproic acid
・ Aminocarb
・ Aminocarboxymuconate-semialdehyde decarboxylase
・ Aminocoumarin
・ Aminocyclitol
・ Aminocyclopropanecarboxylate oxidase
・ Aminocyclopyrachlor
・ Aminodeoxychorismate lyase
・ Aminodeoxychorismate synthase
・ Aminoethylethanolamine
・ Aminoethylpiperazine
・ Aminoff
・ Aminoglutethimide
・ Aminoglycoside
・ Aminoglycoside N3'-acetyltransferase


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Aminocaproic acid : ウィキペディア英語版
Aminocaproic acid

Aminocaproic acid (also known as Amicar, ε-aminocaproic acid, ε-Ahx, or 6-aminohexanoic acid) is a derivative and analogue of the amino acid lysine, which makes it an effective inhibitor for enzymes that bind that particular residue. Such enzymes include proteolytic enzymes like plasmin, the enzyme responsible for fibrinolysis. For this reason it is effective in treatment of certain bleeding disorders, and it is marketed as Amicar. Aminocaproic acid is also an intermediate in the polymerization of Nylon-6, where it is formed by ring-opening hydrolysis of caprolactam.
==Clinical use==
Aminocaproic acid is used to treat excessive postoperative bleeding, especially after procedures in which a great amount of bleeding is expected, such as cardiac surgery. It can be given orally or intravenously. A meta-analysis found that lysine analogs like aminocaproic acid significantly reduced blood loss in patients undergoing coronary artery bypass grafting.
Aminocaproic acid can also be used to treat the overdose and/or toxic effects of the thrombolytic pharmacologic agents tissue plasminogen activator (commonly known as tPA) and streptokinase.

抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
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